Glypican 3 anticorps (C-Term)
Aperçu rapide pour Glypican 3 anticorps (C-Term) (ABIN307157)
Antigène
Voir toutes Glypican 3 (GPC3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain
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Attributs du produit
- GPC3, GPC-3, OCI5, OCI-5, GTR2-2, MXR7,Glypican-3 encodes a putative extracellular proteoglycan that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. It appears to form a complex with insulin-like growth factor and hence modulate IGF2 action. Glypican-3 is the human homolog of OCI-5, a GPI-linked proteoglycan first isolated from rat intestine. Originally identified as the molecular basis for Simpson-Golabi-Behmel syndrome (SGBS) also called Simpson dysmorphia syndrome (SDYS).
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Purification
- Total IgG
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Immunogène
- C terminal recombinant protein (~70aa) which does not overlap with clone 1G12 epitope)
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Isotype
- IgG
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Indications d'application
- Antibody can be used for immunohistochemistry on paraffin-embedded tissues (10 μg/mL) and Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Glypican 3 (GPC3)
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Autre désignation
- Glypican-3 (GPC3)
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UniProt
- P51654
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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